Reversing Memory Loss with the Bredesen Protocol
Oct 29, 2021 ● By Jessica Montalvo, MD
Photo by freshidea for Adobe Stock
When Dr. Dale Bredesen, author of The
End of Alzheimer’s, began his work as a researcher in neurology, he was
optimistic that Alzheimer’s disease was curable by a drug. The last new drug
approved was in 2003 because all the medications studied since have failed to
show results in clinical trials. Bredesen’s work tells us why we’ve made so
little progress with Alzheimer’s. At least 36 separate pathways exist that can
lead to the symptoms of Alzheimer’s dementia. A really excellent drug can only
address two or three holes at best, so we have to follow a treatment plan that
is much wider in scope.
The Bredesen Protocol is a new way to think
about memory loss. Our brains start on the path of destruction decades before
we start to visibly lose our memory. If the building blocks of the brain, the
neurons, do not receive the right mix of signals from those 36 pathways, they
die off. Then over time, we develop symptoms of dementia.
Alzheimer’s is the result of a misguided
attempt of the brain to protect itself from a bad environment. The three main
threats are inflammation; a shortage of supportive nutrients, hormones and
other healthy brain materials; and toxic substances such as metals, pesticides
and biotoxins produced by mold or other organisms.
The brain responds to these dangers by
producing a protective substance called amyloid precursor protein, or APP, that
wants to wall off damaged neurons. The brain does not want to spend resources
on sick neurons when it can be strengthening healthy ones. When the threatening environment is
persistent, APP production crosses from protective to harmful, choking off more and more neurons. The result is
loss of memory, function and understanding of the world.
The Bredesen Protocol fixes the insulin
resistance inflammation by focusing on food choices that are low in sugar,
moderate in protein and high in quality fats. This allows the body to produce
less insulin overall, and good fats are a much better source of fuel for brain
cells. The timing of meals is also important. Following an eating schedule
called intermittent fasting helps prevent excessive insulin production.
Brain cells and synapses need hormones such
as estradiol and testosterone; nutrients such as vitamin D, vitamin B12
and folate; and other compounds such as brain-derived neurotrophic factor, or
BDNF. These factors make the building blocks of the brain stronger in the
presence of stress.
The body is usually able
to deal with toxins we encounter daily. Many reactions take place in the liver,
kidneys and gut to make them harmless to be removed through urine, stool or
sweat. Becoming overwhelmed by toxins causes many possible symptoms, including
memory loss. The brain sees toxins as bad, and tries to protect itself by
producing APP.
The Bredesen Protocol
works well for people that want to help prevent Alzheimer’s
or notice symptoms early and seek attention. The myth that Alzheimer’s disease is not preventable or that mild symptoms are not reversible is still pervasive in medical and public opinion. This misinformation can rob people of their ability to take greater control of their health destiny.
or notice symptoms early and seek attention. The myth that Alzheimer’s disease is not preventable or that mild symptoms are not reversible is still pervasive in medical and public opinion. This misinformation can rob people of their ability to take greater control of their health destiny.
For more information, visit AlzSurvivor.com.
Jessica Montalvo, M.D., is a certified functional medicine clinician
through the Institute for Functional Medicine and has completed training in Dr.
Dale Bredesen’s RECODE protocol. She practices at Forum Health, in Wheaton. To
learn more, visit ForumHealth.com/locations/wheaton-il.